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Ovarian Cancer
Part I of Essay
Of all gynecologic malignancies, continues to have the
highest mortality and is the most difficult to diagnose. In the United States
female population, ranks fifth in absolute mortality among
cancer related deaths (13,000/yr). In most reported cases, ,
when first diagno .... Part II of Essay
.... has been associated with
aberrant, dysfunctional expression and/or mutation of various genes. This can
include oncogene overexpression, amplification or mutation, aberrant tumor
suppressor expression or mutation. Also, subversion of host antitumor immune
responses may play a role in the pathogenesis of cancer (Sharp, 77).
Ovarian clear cell adenocarcinoma was first described by Peham in 1899
as "hypernephroma of the ovary" because of its resemblance to renal cell
carcinoma. By 1939, Schiller noted a histologic similarity to meso ....
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Words: 4156 - Pages: 16
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